W   21 - 7 

Behind the hard running of Sedrick Shaw, Iowa moved to 4-0 on the year and 1-0 in the Big Ten by defeating Michigan State 21-7. During a scoreless first quarter, Iowa outgained Michigan State 128 yards to eight in total offense. The Hawkeyes got two second quarter field goals including a 50-yarder by Brion Hurley, but still trailed the Spartans 7-6 at the half. The second half featured the tough running of Shaw, who finished the game with a career high 250 yards rushing on 42 carries. It was the second best one-game performance in Iowa history. Iowa racked up 524 yards of offense, compared to 313 for Michigan State. Matt Sherman threw for 213 yards while completing 13 of 26 passes, six of which went to Tim Dwight for 115 yards. The Iowa defense stymied the Spartan ground attack, allowing only 31 yards for the day. Freshman Vernon Rollins led the team with seven tackles including one for a loss and one fumble recovery. Plez Atkins recorded two interceptions.

	1	2	3	4	F
Iowa	0	6	8	7	21
Michigan State	0	7	0	0	7